Research Interests
We are currently interested in the following topics but are not limited to that:

  • Metadata management for scientific data, such as in the medical domain (e.g., clinical and epidemiological studies) and others
  • Interface descriptions and exchange formats, such as Object Data Model (ODM) and Interoperable Health Environment (IHE), and their application in different scientific domains
  • Scientific OLAP applications including i2b2 and Lens Data Portal (used in the LIFE Data Portal) and their application in Data Sharing scenarios
  • Data Sharing applications
  • Integration and analysis of geo-referenced data, such as from wearables and environmental sensors
  • Data management in Blockchain scenarios

Publications (most recent first)

2021

  • Fluck, J.; Lindstädt, B.; Ahrens, W.; Beyan, O.; Buchner , B.; Darms, J.; Depping, R.; Dierkes, J.; Neuhausen, H.; Müller, W.; Zeeb, H.; Golebiewski, M.; Löffler, M.; Löbe, M.; Meineke, F.; Klammt, S.; Brosteanu, O.; Fröhlich, H.; Hahn, H.; Schulze, M.; Pischon, T.; Nöthlings, U.; Sax, U.; Kusch, H.; Grabenhenrich, L.; Schmidt, C. O.; Waltemath, D.; Semler, S.; Gehrke, J.; Kirsten, T.; Praßer, F.; Thun, S.; Wieler, L.; Pigeot, I. NFDI4Health – Nationale Forschungsdateninfrastruktur für Personenbezogene Gesundheitsdaten. BFDM 2021, 72-85. DOI: https://doi.org/10.17192/bfdm.2021.2.8331
  • Uciteli, Alexandr; Beger, Christoph; Wagner, Jonas; Kirsten, Toralf; Meineke, Frank; Stäubert, Sebastian; Löbe, Matthias; Herre, Heinrich: Ontological modelling and FHIR Search based representation of basic eligibility criteria. GMS Med Inform Biom Epidemiol 2021;17(2):Doc05. doi: 10.3205/mibe000219
  • Welk J: Ableitung von Orten und Wegen aus GPS-Standortdaten. Tagungsband 21. Nachwuchswissenschaftler*innenkonferenz. 2021;225-230.ISBN-13:978-3-932886-36-2
  • Uciteli A, Beger C, Wagner J, Kiel A, Meineke FA, Stäubert S, Löbe M, Hänsel R, Schuster J, Kirsten T, Herre H. Ontological Modelling and Execution of Phenotypic Queries in the Leipzig Health Atlas. Stud Health Technol Inform. 2021 May 24;278:66-74. doi: 10.3233/SHTI210052. PMID: 34042877.
  • Mou, Yonli; Welten, Sascha; Yediel, Yeliz Ucer; Kirsten, Toralf; Beyan, Oya Deniz: Distributed Learning for Melanoma Classification using Personal Health Train. Proc. 31st Medical Informatics Europe Conference (MIE), 2021
  • Thor, Andreas; Kirsten, Toralf: Das E-Assessment-Tool DMT. Datenbank-Spektrum. Springer Verlag. p. 1-8. 2021

2020

  • Marselle, M.R.; Bowler, D.E.; Watzema, Jan; Eichenberg, David; Kirsten, Toralf; Bonn, Aletta: Urban street tree biodiversity and antidepressant prescriptions. Nature Scientific Reports (10): 22445, 2020. https://doi.org/10.1038/s41598-020-79924-5
  • Heuschkel, Marie-Luise; Becker, Sven; Jeraufke, Saskia; Lucas, Christina; Mohaupt, Marleen; Labudde, Dirk; Kirsten, Toralf; Grosskopf, Birgit: Zur Spurensuche an menschlichen Skeletten. In: Seidel, E, Steinheimer, F, Weber, C (Hrsg), Spurenlesen. Methodische Ansätze der Sammlungs- und Objektforschung. (Junges Forum für Sammlungs-und Objektforschung 4, gg. von der Gesellschaft für Universitätssammlungen e.V. Berlin), Berlin. 2020, DOI: 10.18452/22415
  • Uciteli, Alexandr; Beger, Christoph; Kirsten, Toralf; Meineke, Frank A; Herre, Heinrich: Ontological representation, classification and data-driven computing of phenotypes. Journal of Biomedical Semantics, 11(1):1-17, 2020
  • Li, Dian; Rauscher, Franziska G; Choi, Eun Young; Wang, Mengyu; Baniasadi, Neda; Wirkner, Kerstin; Kirsten, Toralf; Thiery, Joachim; Engel, Christoph; Loeffler, Markus; Elze, Tobias: Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness. Ophthalmology, 127(3): 357-368, 2020
  • Baniasadi, Neda; Rauscher, Franziska G; Li, Dian; Wang, Mengyu; Choi, Eun Young; Wang, Hui; Peschel, Thomas; Wirkner, Kerstin; Kirsten, Toralf; Thiery, Joachim; Engel, Christoph; Loeffler, Markus; Elze, Tobias: Norms of interocular circumpapillary retinal nerve fiber layer thickness differences at 768 retinal locations. Translational Vision Science & Technology, 9(9):23, 2020
  • Lefebvre, Gregory; Shevlyakova, Maya; Charpagne, Aline; Marquis, Julien; Vogel, Mandy; Kirsten, Toralf; Kiess, Wieland; Austin, Sean; Sprenger, Norbert; Binia, Norbert: Time of lactation and maternal fucosyltransferase genetic polymorphisms determine the variability in human milk oligosaccharides. Frontiers in nutrition. 7:225, 2020
  • Lin, Ying-Chi ; Christen, Victor; Groß, Anika; Kirsten, Toralf; Domingos Cardoso, Silvio; Pruski, Cédric; Da Silveira, Marcos; Rahm, Erhard: Evaluating Cross-lingual Semantic Annotation for Medical Forms. Proc. 13th International Conference on Health Informatics (HEALTHINF), 145-155, 2020

2019

  • Paech, Christian ; Moser, Janina ; Dähnert, Ingo ; Wagner, Franziska ; Gebauer, Roman ; Kirsten, Toralf ; Vogel, Mandy ; Kiess, Wieland ; Körner, Antje ; Wolfarth, Bernd ; Wüstenfeld, Jan: Different habitus but similar electrocardiogram: Cardiac repolarization parameters in children & Comparison of elite athletes to obese children. Annals of Pediatric Cardiology, 12(3): 201-205. 2019, DOI: 10.4103/apc.APC_90_18
  • Heuschkel, Marie Luise ; Jeraufke, Saskia ; Becker, Sven ; Lucas, Christina ; Mohaupt, Marleen ; Labudde, Dirk ; Kirsten, Toralf: Anthropology, Osteology and Digitization and Developing a Digital “Bones Library” for Anthropological Analyses and The Digitization of Cultural Heritage Objects. Proc. of 13th Meeting of the Society of Anthropology (Gesellschaft für Anthropologie, GfA), Georg-August-Universität Göttingen, 2019
  • Löbe, Matthias; Beyan, Oya; Stäubert, Sebastian; Meineke, Frank; Ammon, Danny; Winter, Alfred; Decker, Stefan; Löffler, Markus; Kirsten, Toralf: Design of Metadata Services for Clinical Data Interoperability in Germany. MedInfo 2019: 1528-1529
  • Li, Dian ; Rauscher, Franziska G. ; Choi, Eun Young ; Wang, Mengyu ; Baniasadi, Neda ; Wirkner, Kerstin ; Kirsten, Toralf ; Thiery, Joachim ; Engel, Christoph ; Loeffler, Markus ; Elze, Tobias: Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness. In: Ophthalmology. https://doi.org/10.1016/j.ophtha.2019.09.019
  • Kabisch, Nadja ; Selsam, Peter ; Kirsten, Toralf ; Lausch, Angela ; Bumberger, Jan: A multi-sensor and multi-temporal remote sensing approach to detect land cover change dynamics in heterogeneous urban landscapes. In: Ecological Indicators 99 (2019), 273–282. http://dx.doi.org/10.1016/j.ecolind.2018.12.033. – DOI: 10.1016/j.ecolind.2018.12.033
  • Schmidt, Ricarda ; Kirsten, Toralf ; Hiemisch, Andreas ; Kiess, Wieland ; Hilbert, Anja: Interview-based assessment of avoidant/restrictive food intake disorder (ARFID): A pilot study evaluating an ARFID module for the Eating Disorder Examination. In: International Journal of Eating Disorders (2019), 388–397. http://dx.doi.org/10.1002/eat.23063. – DOI: 10.1002/eat.23063
  • Eckelt, Felix ; Vogel, Mandy ; Geserick, Mandy ; Kirsten, Toralf ; Bae, Yoon J. ; Baber, Ronny ; Schaab, Michael ; Thiery, Joachim ; Pfaeffle, Roland ; Raue, Friedhelm ; Kiess, Wieland ; Kratzsch, Jürgen: Calcitonin measurement in pediatrics: reference ranges are gender-dependent, validation in medullary thyroid cancer and effects of thyroid diseases . In: Clinical Chemistry and Laboratory Medicine (CCLM) (2019). http: //dx.doi.org/10.1515/cclm-2018-1186. – DOI: 10.1515/cclm–2018–1186

2018

  • Karim, Md ; Nguyen, Binh-Phi ; Zimmermann, Lukas ; Kirsten, Toralf ; Löbe, Matthias ; Meineke, Frank ; Stenzhorn, Holger ; Kohlbacher, Oliver ; Decker, Stefan ; Beyan, Oya: A Distributed Analytics Platform to Execute FHIR-based Phenotyping Algorithms. In: Proc. of the 11th International Conference Semantic Web Applications and Tools for Life Sciences (SWAT4HCLS 2018) Bd. CEUR Workshop Proceedings 2275, 2018
  • Lausch, Angela ; Borg, Erik ; Bumberger, Jan ; Dietrich, Peter ; Heurich, Marco ; Huth, Andreas ; Jung, Andras ; Klenke, Reinhard ; Knapp, Sonja ; Mollenhauer, Hannes ; Paasche, Hendrik ; Paulheim, Heiko ; Pause, Marion ; Schweitzer, Christian ; Schmulius, Christiane ; Settele, Josef ; Skidmore, Andrew ; Wegmann, Martin ; Zacharias, Steffen ; Kirsten, Toralf ; Schaepmann, Michael: Understanding Forest Health with Remote Sensing, Part III: Requirements for a Scalable Multi-Source Forest Health Monitoring Network Based on Data Science Approaches. In: Remote Sensing 10 (2018), Nr. 7, 1120. http://dx.doi.org/10.3390/rs10071120. – DOI 10.3390/rs10071120
  • Treudler, Regina ; Zeynalova, Samira ; Kirsten, Toralf ; Engel, Christoph ; Loeffler, Markus ; Simon, Jan-Christoph: Living in the city centre is associated with type 1 sensitization to outdoor allergens in Leipzig, Germany. In: The Clinical Respiratory Journal (2018).
  • Loeffler-Wirth, Henry ; Vogel, Mandy ; Kirsten, Toralf ; Glock, Fabian ; Poulain, Tanja ; Körner, Antje ; Loeffler, Markus ; Kiess, Wieland ; Binder, Hans: Longitudinal anthropometry of children and adolescents using 3D-body scanning. In: PloS one 13 (2018), Nr. 9, S. e0203628
  • Elze, Tobias ; Wang, Mengyu ; Baniasadi, Neda ; Wang, Hui ; Li, Dian ; Wirkner, Kerstin ; Kirsten, Toralf ; Enzenbach, Cornelia ; Nüchter, Matthias ; Thiery, Joachim ; Loeffler, Markus ; Engel, Christoph ; Rauscher, Franziska G.: Zones of circumpapillary retinal never fiber layer thickness (cpRNFLT)(in-) vulnerability to aging and life style. In: Investigative Ophthalmology & Visual Science 59 (2018), Nr. 9, S. 1101–1101
  • Winter, Alfred ; Stäubert, Sebastian ; Ammon, Danny ; Aiche, Stephan ; Beyan, Oya ; Bischoff, Verena ; Philipp Daumke and, Stefan D. ; Funkat, Gert ; Gewehr, Jan E. ; Greiff, Armin de ; Haferkamp, Silke ; Hahn, Udo ; Henkel, Andreas ; Kirsten, Toralf ; Klöss, Thomas ; Lippert, Jörg ; Löbe, Matthias ; Lowitsch, Volker ; Maassen, Oliver ; Maschmann, Jens ; Meister, Sven ; Mikolajczyk, Rafael ; Nüchter, Matthias ; Pletz, Mathias W. ; Rahm, Erhard ; Riedel, Morris ; Saleh, Kutaiba ; Schuppert, Andreas ; Smers, Stefan ; Stollenwerk, Andre ; Uhlig, Stefan ; Wendt, Thomas ; Zenker, Sven ; Fleig, Wolfgang ; Marx, Gernot ; Scherag, Andre ; Loeffler, Markus: Smart Medical Information Technology for Healthcare (SMITH). In: Methods of Information in Medicine 57 (2018), Nr. S 01, S. e92–e1
  • Twrdik, Alexander; Braumann, Ulf-Dietrich; Abicht, Franziska; Kiess, Wieland; Kirsten, Toralf: Measuring Finger Lengths from 2D Palm Scans. In: Proc. Workshop Bildverarbeitung in der Medizin (BVM), 2018

2017

  • Wang, Mengyu; Elze, Tobias; Li, Dian; Baniasadi, Neda; Wirkner, Kerstin; Kirsten, Toralf; Thiery, Joachim; Loeffler, Markus; Engel, Christoph; Rauscher, Franziska G.: Age, ocular magnification, and circumpapillary retinal nerve fiber layer thickness. In: Journal of Biomedical Optics 22 (2017), Nr. 12, 121718. http://dx.doi.org/10.1117/1.JBO.22.12.121718. – DOI 10.1117/1.JBO.22.12.121718
  • Loeffler-Wirth, Henry; Vogel, Mandy; Kirsten, Toralf; Glock, Fabian; Poulain, Tanja; Körner, Antje; Loeffler, Markus; Kiess, Wieland; Binder, Hans: Crosssectional and longitudinal body typing of children and adolescents using 3D-body scanning. In: PloS one 12 (2017), Nr. 10. http://dx.doi.org/10.1371/journal.pone.0186881. – DOI 10.1371/journal.pone.0186881
  • Paech, Christian; Liebold, Anja; Gebauer, Roman A.; Wagner, F.; Vogel, Mandy; Kirsten, Toralf; Schauff, M; Hiemisch, Andreas; Dähnert, Ingo; Kiess, Wieland; Körner, Antje: Relative QT interval prolongation and electrical inhomogeneity of cardiac repolarization in childhood obesity. In: Progress in Pediatric Cardiology (2017). http://dx.doi.org/10.1016/j.ppedcard.2017.08.001. – DOI 10.1016/j.ppedcard.2017.08.001
  • Paech, Christian; Anhalt, M.; Gebauer, Roman A.; Wagner, F.; Vogel, Many; Kirsten, Toralf; Weidenbach, M.; Kiess, Wieland; Dähnert, Ingo; Körner, Antje: New normal limits for pediatric ECG in childhood obesity? Influence of childhood obesity on the ECG. In: Progress in Pediatric Cardiology (2017). http://dx.doi.org/10.1016/j.ppedcard.2017.11.002. – DOI 10.1016/j.ppedcard.2017.11.002
  • Vogel, Mandy; Kirsten, Toralf; Kratzsch, Jürgen; Engel, Christoph; Kiess, Wieland: A combined approach to generate laboratory reference intervals using unbalanced longitudinal data. In: Journal of Pediatric Endocrinology and Metabolism 30 (2017), Nr. 7, S. 767–773. http://dx.doi.org/10.1515/jpem-2017-0171. – DOI 10.1515/jpem–2017–0171
  • Lin, Ying-Chi; Groß, Anika; Kirsten, Toralf: Integration and visualization of spatial data in LIFE. In: it-Information Technology (2017). http://dx.doi.org/10.1515/itit-2016-0025. – DOI 10.1515/itit–2016–0025. – ISSN 1611–2776
  • Poulain, Tanja; Baber, Ronny; Vogel, Mandy; Pietzner, Diana; Kirsten, Toralf; Jurkutat, Anne; Hiemisch, Andreas; Hilbert, Anja; Kratzsch, Jürgen; Thiery, Joachim; Fuchs, Michael; Hirsch, Christian; Rauscher, Franziska G.; Loeffler,Markus; Körner, Antje; Nüchter, Matthias; Kiess, Wieland: The LIFE Child study: a population-based perinatal and pediatric cohort in Germany. In: European Journal of Epidemiology 32 (2017), Nr. 2, 145–158. http://dx.doi.org/10.1007/s10654-016-0216-9. – DOI 10.1007/s10654–016–0216–9. – ISSN 1573–7284
  • Glock, Fabian; Vogel, Mandy; Naumann, Stephanie; Kuehnapfel, Andreas; Scholz, Markus; Hiemisch, Andreas; Kirsten, Toralf; Rieger, Kristin; Körner, Antje; Loeffler, Markus; Kiess, Wieland: Validity and intraobserver reliability of three-dimensional scanning compared with conventional anthropometry for children and adolescents from a population-based cohort study. In: Pediatr Res (2017). http://dx.doi.org/10.1038/pr.2016.274. – DOI 10.1038/pr.2016.274
  • Kirsten, Toralf; Kiel, Alexander; Wagner, Jonas; Rühle, Mathias; Löffler, Markus: Selecting, Packaging, and Granting Access for Sharing Study Data – Experiences from the LIFE Study. In: Proc. Workshop Digitale Prozesse und Informationssysteme im Forschungsdatenmanagement, Jahreskongress INFORMATIK 2017, GI Lecture Notes in Informatics (LNI), 2017
  • Eckelt, Felix; Vogel, Mandy; Geserick, Mandy; Kirsten, Toralf; Bae, Yoon J.; Schaab, Michael; Körner, Antje; Hiemisch, Andreas; Thiery, Joachim; Pfaeffle, Roland; Kiess, Wieland; Raue, Friedhelm; Kratzsch, Jürgen: Determination of Calcetonin Reference Ranges from Healthy Infants, Children and Adolescents – an important Tool for the early Diagnosis of medullary Thyroid Cancer. In: Proc. 10th International Meeting of Pediatric Endocrinology Bd. 88, 2017, S. 40
  • Wang, Mengyu; Mengyu, Tobias; Li, Dian; Baniasadi, Neda; Wirkner, Kerstin; Kirsten, Toralf; Nüchter, Matthias; Thiery, Joachim; Loeffler, Markus; Engel, Christoph; Rauscher, Franziska: The Relationship between the Full Circumpapillary Retinal Nerve Fiber Layer Thickness (RNLFT) Profile and Age in Healthy Subjects. In: Abstract Proc. Intl. ARVO Imaging in the Eye Conference, 2017
  • Kirsten, Toralf; Kiel, Alexander; Rühle, Mathias; Wagner, Jonas: Metadata Management for Data Integration in Medical Sciences – Experiences from the LIFE Study. In: Proc. 17. Fachtagung Datenbanksysteme für Business, Technologie und Web (BTW), GI Lecture Notes in Informatics (LNI), 2017

2016

  • Sax, Ulrich; Bauer, Christian; Ganslandt, Thomas; Kirsten, Toralf: Forschungsdatenmanagement. In: IT-Infrastrukturen in der patientenorientierten Forschung – Aktueller Stand und Handlungsbedarf (2016). http://www.tmf-ev.de/Produkte/ITReport.aspx
  • Reinhold, Olaf; Wittwer, Matthias; Alt, Rainer; Kirsten, Toralf; Kiess, Wieland: Exploring the Context from the Consumer Perspective: Insights from the eBusiness and Health Care. In: Proc. Intl. Workshop on Integrative Analysis and Computation of Life Data for Smart Ecosystems, attached at the International Conference on Business Information Systems, Springer Lecture Notes in Business Information Processing (LNBIP), 2016
  • Kirsten, Toralf; Bumberger, Jan; Ivanova, Galina; Dietrich, Peter; Engel, Christoph; Löffler, Markus; Kiess, Wieland: On integrating health and environmental data in epidemiological studies. In: Proc. Intl. Workshop on Integrative Analysis and Computation of Life Data for Smart Ecosystems, attached at the International Conference on Business Information Systems, Springer Lecture Notes in Business Information Processing
    (LNBIP), 2016
  • Lin, Ying-Chi; Groß, Anika; Kirsten, Toralf: Integration and visualization of spatial data in LIFE. In: Proc. Workshop Data Integration in the Life Sciences, attached at the HEC, 2016

2015

  • Uciteli, Alexandr; Kirsten, Toralf: Ontology-based retrieval of scientific data in LIFE. In: Proc. Workshop on Data Management for Life Sciences: 16. Fachtagung Datenbanksysteme für Business, Technologie und Web (BTW), GI Lecture Notes in Informatics (LNI), 2015

2014

  • Girlich, Friederike; Stein, Robert; Henger, Sylvia; Uciteli, Alexandr; Engel, Christoph; Löffler, Markus; Kirsten, Toralf: Zentrales Datenmanagement im Leipziger Forschungszentrum für Zivilisationserkrankungen: Überblick über Prozesse und Methoden. In: Abstract Proc. of 58. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), 2014
  • Uciteli, Alexandr; Kirsten, Toralf: Ontologie-basierter Export von Forschungsdaten in LIFE. In: Abstract Proc. of 58. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), 2014
  • Vogel, Mandy; Kirsten, Toralf; Fischer, Anna-Lena ; Kiess, Wieland: Standard Deviation Scores in Data Quality Control of Age-dependent Measurement Values. In: Abstract Proc. of 58. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), 2014

2013

  • Kirsten, Toralf; Kiel, Alexander; Kleinert, Michael; Speer, Ronald; Engel, Christoph; Löffler, Markus: Forschungsdaten- und Probandenmanagement in LIFE. In: Abstract Proc. of 58. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), 2013

2012

  • Groß, Anika; Hartung, Michael; Kirsten, Toralf; Rahm, Erhard: GOMMA Results for OAEI 2012. In: Proc. of 7th Intl. Workshop on Ontology Matching, in Begleitung der ISWC, 2012
  • Hartung, Michael; Groß, Anika; Kirsten, Toralf; Rahm, Erhard: Effective Mapping Composition for Biomedical Ontologies. In: Proc. of Intl. Workshop on Semantic Interoperability in Medical Informatics, in Begleitung der ESWC, 2012
  • Meineke, Frank; Stäubert, Sebastian; Kirsten, Toralf: Medizinische Forschungsdatenbanken als Baustein des Forschungsdatenmanagements an der Universität Leipzig. In: Abstract Proc. of 57. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), 2012

2011

  • Kirsten, Toralf; Groß, Anika; Hartung, Michael; Kolb, Lars; Rahm, Erhard: GOMMA: A Component-based Infrastructure for managing and analyzing Life Science Ontologies and their Evolution. In: Journal of Biomedical Semantics (2011), Nr. 6
  • Groß, Anika; Hartung, Michael; Kirsten, Toralf; Rahm, Erhard: Mapping Composition for Matching Large Life Science Ontologies. In: Proc. of 2nd Intl. Conference on Biomedical Ontology (ICBO), 2011

2010

  • Bermudez-Santana, Clara; Attolini, Camille Stephan-Otto; Kirsten, Toralf; Engelhardt, Jan; Prohaska, Sonja J.; Steigele, Stephan; Stadler, Peter F.: Genomic organization of eukaryotic tRNAs. In: BMC Genomics 11 (2010), S. 270
  • Kirsten, Toralf; Kolb, Lars; Hartung, Michael; Groß, Anika; Rahm, Erhard: Data Partitioning for Parallel Entity Matching. In: Proc. 8th Intl. Workshop on Quality in Databases, in Begleitung der VLDB 2010, 2010
  • Groß, Anika; Hartung, Michael; Kirsten, Toralf; Rahm, Erhard: On Matching Large Life Science Ontologies in Parallel. In: Proc. 7th Intl. Conference on Data Integration in the Life Sciences (DILS), Springer Lecture Notes in Bioinformatics (LNBI), 2010
  • Hartung, Michael; Groß, Anika; Kirsten, Toralf; Rahm, Erhard: Discovering Evolving Regions in Life Science Ontologies. In: Proc. 7th Intl. Conference on Data Integration in the Life Sciences, Springer Lecture Notes in Bioinformatics (LNBI), 2010
  • Kirsten, Toralf; Kiel, Alexander: Ontology-based Registration of Entities for Data Integration in large biomedical Research Projects. In: Proc. Workshop Information Integration in Service Architectures (IISA), in Begleitung der INFORMATIK 2010, 2010

2009

  • Hartung, Michael; Kirsten, Toralf; Groß, Anika; Rahm, Erhard: OnEX: Exploring Changes in Life Science Ontologies. In: BMC Bioinformatics 10 (2009), S. 250
  • Kirsten, Toralf; Hartung, Michael; Groß, Anika; Rahm, Erhard: Efficient Management of biomedical Ontology Versions. In: Proc. 4th Intl. Workshop of Ontology Content (OnToContent), 2009
  • Groß, Anika; Hartung, Michael; Kirsten, Toralf; Rahm, Erhard: Estimating the Quality of ontology-based Annotations by considering evolutionary Changes. In: Proc. 6th Intl. Workshop on Data Integration in the Life Sciences (DILS), Springer Lecture Notes in Bioinformatics (LNBI), 2009
  • Thor, Andreas; Hartung, Michael; Groß, Anika; Kirsten, Toralf; Rahm, Erhard: An evolution-based approach for assessing ontology mappings – A case study in the life sciences. In: Proc. 13. GI-Fachtagung Datenbanksysteme für Business, Technologie und Web (BTW), GI Lecture Notes in Informatics (LNI), 2009

2008

  • Lindemeyer, Manja; Kirsten, Toralf; Stadler, Peter: Molecular evolution of spliceosomal snRNA genes in Metazoan animals. In: Journal of Molecular Evolution (2008)
  • Hartung, Michael; Kirsten, Toralf; Rahm, Erhard: Analyzing the Evolution of Life Science Ontologies and Mappings. In: Proc. 5th Intl. Workshop on Data Integration in the Life Sciences (DILS), Springer Lecture Notes in Bioinformatics (LNBI), 2008

2007

  • Rahm, Erhard; Kirsten, Toralf; Lange, Jörg: The GeWare data warehouse platform for the analysis of molecular-biological and clinical data. In: Journal of Integrative Bioinformatics 4 (2007), Nr. 1, S. 47
  • Thor, Andreas; Kirsten, Toralf; Rahm, Erhard: Instance-based matching of hierarchical ontologies. In: Proc. 12. GI-Fachtagung Datenbanksysteme für Business, Technologie und Web (BTW), GI Lecture Notes in Informatics (LNI), 2007
  • Kirsten, Toralf; Thor, Andreas; Rahm, Erhard: Instance-based matching of large life science ontologies. In: Proc. 4th Intl. Workshop on Data Integration in the Life Sciences (DILS), Springer Lecture Notes in Bioinformatics (LNBI), 2007

2006

  • Kirsten, Toralf; Lange, Jörg; Rahm, Erhard: An integrated platform for analyzing molecular–biological data within clinical studies. In: Proc. of the Intl. EDBT Workshop on Information Integration in Healthcare Applications (IIHA), 2006, S. 399–410
  • Kirsten, Toralf; Rahm, Erhard: BioFuice: Mapping–based data integration in bioinformatics. In: Proc. of the 3rd Intl. Workshop on Data Integration in the Life Sciences (DILS), Springer Lecture Notes in Bioinformatics (LNBI), 2006, S. 124–135
  • Lange, Jörg; Kirsten, Toralf; Rahm, Erhard: An integrated analysis platform for experimental and clinical data in modern cancer research studies. In: Proceedings 51. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS), 2006

2005

  • Binder, Hans; Preibisch, Stephan; Kirsten, Toralf: Base pair interactions and hybridization isotherms of matched and mismatched oligonucleotide probes on microarrays. In: Langmuir 21 (2005), Nr. 20, S. 9287–9302
  • Rahm, Erhard; Thor, Andreas; Aumüller, David; Do, Hong-Hai; Golovin, Nick; Kirsten, Toralf: iFuice – Information fusion utilizing instance-based peer mappings. In: Proc. 8th Intl. Workshop on Web and Databases (WebDB), 2005
  • Kirsten, Toralf; Do, Hong-Hai; Körner, Christine; Rahm, Erhard: Hybrid integration of molecular–biological annotation data. In: Proc. 2nd Intl. Workshop on Data Integration in the Life Sciences (DILS), 2005
  • Körner, Christine; Kirsten, Toralf; Do, Hong-Hai; Rahm, Erhard: Hybride Integration von molekularbiologischen Annotationsdaten. In: Proc. 11. GI-Fachtagung Datenbanksysteme für Business, Technologie und Web (BTW), GI Lecture Notes in Informatics (LNI), 2005

2004

  • Binder, Hans; Kirsten, Toralf; Löffler, Markus; Stadler, Peter F.: Sensitivity of microarray oligonucleotide probes: Variability and effect of base composition. In: Journal Physical Chemistry in the Biology 108 (2004), Nr. 46, S. 18003–18014
  • Binder, Hans; Kirsten, Toralf; Hofacker, Ivo L.; Stadler, Peter F.; Löffler, Markus: Interactions in oligonucleotide hybrid duplexes on microarrays. In: Journal Physical Chemistry in the Biology 108 (2004), Nr. 46, S. 18015–18025

2003

  • Kirsten, Toralf; Do, Hong-Hai; Rahm, Erhard: A multidimensional data warehouse for gene expression analysis. In: Proc. German Conference on Bioinformatics (GCB), Poster Abstract Band, 2003
  • Do, Hong-Hai; Kirsten, Toralf; Rahm, Erhard: Comparative evaluation of microarray–based gene expression databases. In: Proc. 10. GI-Fachtagung Datenbanksysteme für Business, Technologie und Web (BTW), GI Lecture Notes in Informatics (LNI), 2003

2001

  • Kruczynski, Klaus; Kirsten, Toralf: Grundzüge der Data Warehouse Architektur: Die Corporate Information Factory. In: IS report (2001), Nr. 10, S. 36 – 41

2000

  • Kruczynski, Klaus; Kirsten, Toralf: Data Warehouse: Architekturen & Clusterung – Beispiel im eCRM-Kontext. In: Proc. 8. Leipziger Informatik Tage (LIT), 2000